Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | expression_12hrs.Phenotype.cls #treated_versus_cont.Phenotype.cls #treated_versus_cont_repos |
| Phenotype | Phenotype.cls#treated_versus_cont_repos |
| Upregulated in class | cont |
| GeneSet | MSIGDB_C2|BIOCARTA_CTL_PATHWAY |
| Enrichment Score (ES) | -0.90687823 |
| Normalized Enrichment Score (NES) | -1.6621952 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.18820529 |
| FWER p-Value | 0.997 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | 355 | "FAS (Fas (TNF receptor superfamily, member 6))" | 3802 | 7.517 | -0.1630 | No | ||
| 2 | 6955 | TRA@ (T cell receptor alpha locus) | 6571 | 1.704 | -0.2938 | No | ||
| 3 | 915 | "CD3D (CD3d molecule, delta (CD3-TCR complex))" | 8076 | 0.700 | -0.3655 | No | ||
| 4 | 3683 | "ITGAL (integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide))" | 9123 | 0.352 | -0.4159 | No | ||
| 5 | 356 | "FASLG (Fas ligand (TNF superfamily, member 6))" | 9155 | 0.344 | -0.4163 | No | ||
| 6 | 5551 | PRF1 (perforin 1 (pore forming protein)) | 9314 | 0.302 | -0.4231 | No | ||
| 7 | 919 | CD247 (CD247 molecule) | 9865 | 0.167 | -0.4497 | No | ||
| 8 | 3002 | "GZMB (granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1))" | 10454 | 0.024 | -0.4785 | No | ||
| 9 | 917 | "CD3G (CD3g molecule, gamma (CD3-TCR complex))" | 14522 | -1.255 | -0.6747 | No | ||
| 10 | 3689 | "ITGB2 (integrin, beta 2 (complement component 3 receptor 3 and 4 subunit))" | 15270 | -1.772 | -0.7058 | No | ||
| 11 | 916 | "CD3E (CD3e molecule, epsilon (CD3-TCR complex))" | 16842 | -3.845 | -0.7708 | No | ||
| 12 | 3383 | ICAM1 (intercellular adhesion molecule 1) | 17688 | -6.391 | -0.7918 | Yes | ||
| 13 | 3105 | "HLA-A (major histocompatibility complex, class I, A)" | 20027 | -65.132 | -0.6971 | Yes | ||
| 14 | 567 | B2M (beta-2-microglobulin) | 20305 | -220.982 | 0.0010 | Yes |
